Department of Chemistry, A D P College was established along with the initiation of science stream on August, 1978 under the headship of Prof. Mrs. M. Goswami. Later it was headed by Prof. A. H. Choudhury till 2011. The major course was started in 2002. Since its introduction, it fulfills a major problem amongst science students. It is providing quality education in Chemistry in the middle part of Assam. Today, the department attracts students from all parts of the Nagaon district, as well as from other nearby districts like Morigaon, Golaghat and Karbi Anglong etc.
The Department of Chemistry is a full-fledged department with four permanent teaching staff. The last few years have seen substantial changes in the composition of the teaching staff, with many teachers retiring, and new teachers joining in their place. During last two years the department has three permanent teachers but one has retired and one new teacher has joined in his place.